Table 1.
Treatment
GroupsDose (mg/kg)RouteVolume (mL)Frequency
hCRF (high dose)0.1s.c.0.05Twice daily
hCRF (low dose)0.03s.c.0.05Twice daily
DEX (high dose)1s.c.0.1Twice daily
DEX (low dose)0.3s.c.0.1Twice daily
TMZ40i.p.0.2Daily, 5 d/wk
TMZ + hCRF combination (high dose)40 + 0.1i.p. + s.c.Daily, 5 d/wk + twice daily
TMZ + hCRF combination (low dose)40 + 0.03i.p. + s.c.Daily, 5 d/wk + twice daily
Control (vehicle)Daily

Abbreviations: DEX, dexamethasone; TMZ, temozolomide.